Dear Substack readers,
In the realm of cannabinoid research, one name stands out: Dr. Raphael Mechoulam. Often hailed as the "Father of THC," his groundbreaking work has transformed our understanding of the cannabis plant and its potential to revolutionize medicine. In an interview with Dr. Mechoulam for our documentary, “NECTARBALL: The Story of Cannabis,” Patty and Mark gained insights into his profound contributions and the exciting possibilities that lie ahead.
Separating Medical and Recreational Cannabis
In an era of changing cannabis laws and perceptions, Dr. Mechoulam emphasized the distinction between medical and recreational cannabis. He pointed out that legalizing recreational cannabis is a social decision, while the medical benefits of cannabinoids deserve separate recognition. Dr. Mechoulam advocated for a clear separation between the two, acknowledging that they serve distinct purposes in society.
Unveiling Unique Cannabinoid Assets
Dr. Mechoulam and his team embarked on a journey to explore lesser-known cannabinoids and their potential therapeutic applications. He began his research on the chemistry and pharmacology of cannabinoids in 1963. In 1988, he and his team discovered the Endocannabinoid System, which regulates all other systems in the body. The reason ECS is not taught in Medical School here in the USA is because Cannabis has been was listed as a Schedule 1 dangerous drug in 1970 by none other than criminal president Dick Nixon.
A Platform for Research and Discovery
Dr. Mechoulam's important work has led to the development of a platform that grants researchers access to synthetic cannabinoids. This initiative aims to accelerate scientific exploration and facilitate the discovery of novel treatments. By making these compounds available, researchers worldwide can contribute to the growing body of knowledge surrounding cannabinoids.
A Hopeful Vision for Cannabinoids
One of the most exciting prospects discussed was the potential for cannabinoids to replace opioids and other central nervous system drugs.
We are not mice. Something that we see in a mouse does not necessarily have to be the same in humans. I believe that these are important compounds. Possibly somebody will reach at some point a semi-synthetic cannabinoid, which is as potent as narcotics that we use today and it will be less dangerous. And I believe that we can do that. It may take a few years, possibly the government or Food and Drug Administration, or other US agency, to try to push research, particularly clinical trials.
Navigating Political Landscapes
Dr. Mechoulam acknowledged the historical political landscape surrounding cannabis, including its classification as a controlled substance.
Whatever has been said many years ago, we should start looking at the data we have and go ahead and the data is quite positive. I'm not speaking about people that have come up with all kinds of public relation things to say that it can or cannot be effective in essentially all diseases. That's silly. We have to take that data. We have to add to this data. I believe that here we have something very promising, but we should not just go beyond it without the modern clinical trials needed.
Dr. Mechoulam's groundbreaking contributions and unwavering commitment to advancing cannabinoid research offer hope for a brighter and healthier future. His dedication to understanding the intricacies of cannabis and its potential medical applications is inspirational to many who benefit from the medicinal qualities of the plant.
Dr. Mechoulam appears in our documentary, “NECTARBALL: The Story of Cannabis” which has its World Premiere on October 20, 2023.